In Vitro and In Vivo Evaluation of ACE-Inhibitory Activity of Peptides from Seaweeds

This research focuses on the extraction, purification, and characterization of bioactive peptides from various species of marine seaweeds. The study evaluates the angiotensin-converting enzyme (ACE) inhibitory potential of these peptides through both in vitro enzymatic assays and in vivo animal model studies. Key Highlights: - Identification of novel ACE-inhibitory peptides from marine algae - In vitro IC50 determination for purified peptide fractions - In vivo validation using spontaneously hypertensive rat models - Structure-activity relationship analysis - Potential application in functional food development This project contributes to the growing field of marine pharmacology and nutraceutical research, offering natural alternatives for hypertension management.